Last Updated on September 2, 2019

Overview

Lion’s Mane (Hericium erinaceus) is a medicinal mushroom with nootropic qualities. Currently, the research on Lion’s Mane is still in it’s early stages, though it shows a lot of promise and more research is urgently needed. It appears to be most effective for restoring and maintaining proper brain health, which can produce a wide range of benefits.

Lion’s Mane is most commonly referenced for its ability to significantly increase  the expression of nerve growth factor (NGF) [100]. NGF is a molecule produced in the brain that is involved in the regulation of growth, maintenance, proliferation, and survival of neurons. These mushroom may also enhances the formation of myelin and the production of the myelin sheath (myelination) [101][104], promotes neurite outgrowth [102][103] and peripheral nerve regeneration [109]. Supplementation of these mushrooms may also provide neuroprotection against neuronal death [105][106], helps prevent β-amyloid pigmentation [107].

Overall it’s quite effective for maintaining cognitive ability over time, keeping the mind sharp and healthy [108].

Recent research has indicated that supplementation may also provide gastrointenstinal benefits, especially to the colon and stomach [110][111].

 

Lion’s Mane Dosage Information

Lion’s Mane does not have a standard dosage, however one human trial show efficacy with 1000mg doses taken 3x daily, and total daily doses of 3000mg or more may be optimal. It does not need to be taken with meals.

 

Where to Buy Lion’s Mane Mushrooms

Buy Lion’s Mane Capsules at Nootropics Depot [Vendor Info]

 

 

 

References

100. https://www.ncbi.nlm.nih.gov/pubmed/18758067

101. http://www.dl.begellhouse.com/journals/708ae68d64b17c52,0d49dda96a2a7147,504922782f5fa5ea.html

102. https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-13-261

103. https://pubs.rsc.org/en/content/articlelanding/2014/fo/c4fo00452c/unauth#!divAbstract

104. https://www.ncbi.nlm.nih.gov/pubmed/12675022

105. https://www.ncbi.nlm.nih.gov/pubmed/19661683

106. https://www.ncbi.nlm.nih.gov/pubmed/18835171

107. https://www.ncbi.nlm.nih.gov/pubmed/21383512

108. https://www.ncbi.nlm.nih.gov/pubmed/18844328

109. https://www.ncbi.nlm.nih.gov/pubmed/21941586

110. https://www.ncbi.nlm.nih.gov/pubmed/23668749

111. https://www.hindawi.com/journals/ecam/2013/492976/abs/

 

 

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